Rosales, Adrianne Ph.D.

Assistant Professor

Rosales

Office: CPE 3.418 Mailing Address:
Phone: (512) 471-6300 University of Texas at Austin
Fax: TBD McKetta Department of Chemical Engineering
Email: arosales@che.utexas.edu 200 E Dean Keeton St. Stop C0400
UT Mail: C0400 Austin, Texas  78712-1589

Research Areas: Advanced Materials, Polymers & Nanotechnology, and Biotechnology

Research Group Website (TBD)

Research Presentation for Prospective Graduate Students (TBD)

Educational Qualifications

Postdoctoral Research Fellow, University of Colorado, Boulder (2013 – 2017)
Ph.D., Chemical Engineering, University of California, Berkeley (2013)
B.S., Chemical Engineering, University of Texas at Austin (2007)

Courses Taught

CHE 372 – Reactor

Focus

Biomolecular and biomimetic materials, hydrogel development, cell-matrix interactions, dynamic materials

Research

We study and develop dynamic polymer systems to engineer complex biological microenvironments. In processes such as disease or tissue development, there is an active interplay between cells, the extracellular matrix, and precise chemical and physical signals that change over time. Engineered materials that capture these dynamic properties can shed insight to biological mechanisms and address problems in human health. Using principles from chemical engineering, materials science, and biology, we pursue the following research goals:

  • Fundamental understanding of polymer structure-property relationships, especially biomimetic and stimuli-responsive polymers
  • Development of synthetic hydrogels that actively probe cell-matrix interactions
  • Engineering new material platforms for disease models

Awards & Honors

  • Burroughs Wellcome Fund Career Award at the Scientific Interface (CASI), 2016-2021
  • University of Washington Distinguished Young Scholars Seminar series, 2015
  • NIH Ruth L. Kirschstein NRSA F32 Postdoctoral Fellowship, 2014-2016
  • Burroughs Wellcome Fund Postdoctoral Enrichment Program Award, 2014-2016
  • University of California Dissertation Year Fellowship, 2012
  • National Science Foundation Graduate Fellowship, 2007
  • University of California, Berkeley, Chancellor’s Fellowship, 2007

 Selected Publications

  • A.M. Rosales and K.S. Anseth. “Capturing Extracellular Matrix Dynamics with Reversible Hydrogels.” Nature Reviews Materials, 2016, 1, 15012.
  • A.M. Rosales, K.M. Mabry, E.M. Nehls, K.S. Anseth. “Photoresponsive Elastic Properties of
    Azobenzene-Containing Poly(ethylene-glycol)-based Hydrogels.” Biomacromolecules 2015, 16(3), 798-806.
  • A.M. Rosales, R.A. Segalman, R.N. Zuckermann. “Polypeptoids: A Model System to Study the Effect of Monomer Sequence on Polymer Properties and Self-Assembly.” Soft Matter 2013, 9, 8400-8414.
  • H.K. Murnen*, A.M. Rosales*, A.V. Dobrynin, R.N. Zuckermann, R.A. Segalman. “Persistence Length of Polyelectrolytes with Precisely Located Charges.” Soft Matter 2013, 9, 90-98.
  • A.M. Rosales, B.L. McCulloch, R.N. Zuckermann, R.A. Segalman. “Tunable Phase Behavior of Polystyrene-Polypeptoid Block Copolymers” Macromolecules 2012, 45(15),6027-6035
  • A.M. Rosales, H.K. Murnen, S.R. Kline, R.N. Zuckermann, R.A. Segalman. “Measurement of the Persistence Length of Helical and Non-Helical Polypeptoids in Solution.” Soft Matter 2012, 8, 3673-3680.