Welcome to
the McKetta Department of
Chemical Engineering

#5

Undergraduate Chemical Engineering Program

$2.2M

Awarded in Scholarships

#7

Graduate Chemical Engineering Program

Spotlights

Explore more at the McKetta Department of Chemical Engineering

Adrianne Rosales

Research Group Website

Educational Qualifications

Postdoctoral Research Fellow, University of Colorado, Boulder (2013 – 2017)
Ph.D., Chemical Engineering, University of California, Berkeley (2013)
B.S., Chemical Engineering, University of Texas at Austin (2007)

Courses Taught

CHE 372 – Reactor

Focus

Biomolecular and biomimetic materials, hydrogel development, cell-matrix interactions, dynamic materials

Research

We study and develop dynamic polymer systems to engineer complex biological microenvironments. In processes such as disease or tissue development, there is an active interplay between cells, the extracellular matrix, and precise chemical and physical signals that change over time. Engineered materials that capture these dynamic properties can shed insight to biological mechanisms and address problems in human health. Using principles from chemical engineering, materials science, and biology, we pursue the following research goals:

  • Fundamental understanding of polymer structure-property relationships, especially biomimetic and stimuli-responsive polymers
  • Development of synthetic hydrogels that actively probe cell-matrix interactions
  • Engineering new material platforms for disease models

Awards & Honors

  • Burroughs Wellcome Fund Career Award at the Scientific Interface (CASI), 2016-2021
  • University of Washington Distinguished Young Scholars Seminar series, 2015
  • NIH Ruth L. Kirschstein NRSA F32 Postdoctoral Fellowship, 2014-2016
  • Burroughs Wellcome Fund Postdoctoral Enrichment Program Award, 2014-2016
  • University of California Dissertation Year Fellowship, 2012
  • National Science Foundation Graduate Fellowship, 2007
  • University of California, Berkeley, Chancellor’s Fellowship, 2007

 Selected Publications

  • A.M. Rosales and K.S. Anseth. “Capturing Extracellular Matrix Dynamics with Reversible Hydrogels.” Nature Reviews Materials, 2016, 1, 15012.
  • A.M. Rosales, K.M. Mabry, E.M. Nehls, K.S. Anseth. “Photoresponsive Elastic Properties of
    Azobenzene-Containing Poly(ethylene-glycol)-based Hydrogels.” Biomacromolecules 2015, 16(3), 798-806.
  • A.M. Rosales, R.A. Segalman, R.N. Zuckermann. “Polypeptoids: A Model System to Study the Effect of Monomer Sequence on Polymer Properties and Self-Assembly.” Soft Matter 2013, 9, 8400-8414.
  • H.K. Murnen*, A.M. Rosales*, A.V. Dobrynin, R.N. Zuckermann, R.A. Segalman. “Persistence Length of Polyelectrolytes with Precisely Located Charges.” Soft Matter 2013, 9, 90-98.
  • A.M. Rosales, B.L. McCulloch, R.N. Zuckermann, R.A. Segalman. “Tunable Phase Behavior of Polystyrene-Polypeptoid Block Copolymers” Macromolecules 2012, 45(15),6027-6035
  • A.M. Rosales, H.K. Murnen, S.R. Kline, R.N. Zuckermann, R.A. Segalman. “Measurement of the Persistence Length of Helical and Non-Helical Polypeptoids in Solution.” Soft Matter 2012, 8, 3673-3680.
 

Research Areas

  • woman at desk holding piece of film Advanced Materials, Polymers & Nanotechnology

    Design and synthesis of inorganic and polymeric materials at the molecular level to achieve desirable properties for a wide range of applications

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  • person in lab wearing gloves holding pipette Biotechnology

    Applying chemical engineering principles for the development of biochemical processes and biomedical applications

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  • man in lab wearing orange glasses holding light Energy

    The development of photovoltaics, catalysts for fuels from sunlight, and electrical energy generation and storage systems engineering for energy efficiency

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  • three people in lab coats looking at beaker Environmental Engineering

    Programs to understand the fundamental science and engineering of air and water pollution, and to develop data for informed policy decisions. Process development for CO2 capture and sequestration

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  • woman and man looking and pointing at computer screen Modeling & Simulation

    The development and application of multiscale models and high performance computational simulations spanning atomic to continuum time and length scales

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  • close up of hands holding computer chip plugged in Process Engineering

    Design, modeling, optimization, and control of petrochemical, pharmaceutical, and microelectronic processes

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Membership in the National Academy of Engineering is one of the highest professional distinctions for an engineer, honoring those who have made outstanding contributions to engineering research and practice, including pioneering of new and developing fields of technology and making major advancements in engineering. In 2021, Rachel Segalman joins 106 new members and 23 foreign members elected.

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